Sidenote by AsapSCIENCE

Greg Brown and Mitchell Moffit built a massive audience on YouTube as AsapSCIENCE, and their podcast Sidenote brings that same energy to a longer, more conversational format. Since launching in 2018, the show has become a space where the two Canadian hosts pick a science-adjacent topic — often something controversial or counterintuitive — and spend 40 to 55 minutes breaking down what the research actually says. The vibe is two friends who happen to be science communicators sitting down to hash out questions like whether breakfast really is the most important meal of the day, or what the science says about personality tests. They pull from peer-reviewed studies and mix in personal anecdotes, which keeps things grounded and relatable. The humor is natural and unforced, and their chemistry after years of working together comes through clearly. With 312 episodes and a 4.9 star average from over 2,200 ratings, Sidenote has found a loyal audience that appreciates the blend of entertainment and education. Episodes drop roughly every week or two. The biology content shows up frequently — genetics, nutrition, neuroscience, and human physiology are all regular territory. Some listeners have noted that the show occasionally prioritizes entertainment over strict scientific precision, and that's a fair observation. But for most topics, Greg and Mitch do a solid job of citing their sources and acknowledging uncertainty. It's an accessible entry point for people who want science in their podcast rotation without the academic density.