The Natural State with Dr. Anthony Gustin

Dr. Anthony Gustin is a sports medicine clinician and the founder of Perfect Keto, one of the most recognized keto supplement brands in the market. His podcast takes a broader view than the brand might suggest, exploring what it means to reclaim health by rebuilding a proper human environment in a world that increasingly works against our biology. That framing sets the show apart from podcasts that focus narrowly on macros and ketone levels. The Natural State has over 200 episodes featuring long-form interviews with physicians, researchers, regenerative farmers, mental health practitioners, and fellow entrepreneurs. Conversations tend to run 50 to 75 minutes, giving topics real space to breathe. Gustin has hosted discussions on regenerative agriculture, the health effects of seed oils, ancestral eating patterns, mental health approaches beyond medication, and the business side of building a health company. The show publishes on a less predictable schedule than some others on this list, sometimes weekly, sometimes with longer gaps. With a 4.8-star average from over 2,700 Apple Podcasts ratings, this is one of the most highly rated shows in the keto-adjacent space. Gustin is a thoughtful interviewer who asks good follow-up questions and isn't afraid of long pauses. The production quality is clean. The show's biggest strength is its willingness to zoom out from strict keto talk and examine the broader systems, food supply, environmental factors, lifestyle design, that determine metabolic health. If you already understand the basics of ketogenic eating and want something that connects the dots to larger questions about how we live and eat, Gustin delivers that perspective consistently.