The Dr. Gabrielle Lyon Show

Dr. Gabrielle Lyon is a Washington University fellowship-trained physician and the founder of Muscle-Centric Medicine, a framework that puts skeletal muscle at the center of health and longevity rather than treating it as an afterthought. Her podcast, now 194 episodes deep with a 4.5-star rating from over 1,000 reviews, has become essential listening for women who want to understand why protein intake, strength training, and metabolic health matter so much more than the scale suggests. The weekly show features long-form interviews with researchers, physicians, and thought leaders across medicine, nutrition, and personal development. Recent episodes have tackled the new dietary guidelines and their emphasis on protein, practical strategies for eating to support metabolism and longevity, and the psychology behind self-belief. Dr. Lyon has a directness that some find refreshing and others find intense -- she does not sugarcoat the consequences of muscle loss as women age, and she is not afraid to challenge popular narratives in the nutrition world. The show is available on both audio platforms and YouTube, and ad-free episodes are offered through her Forever Strong Insider subscription. Her audience includes everyone from busy moms to military special operations personnel, which gives you a sense of the range. If you have heard the phrase "muscle is the organ of longevity" and want the full scientific backing behind it, this is where to go.