The Carlat Psychiatry Podcast

If you want to understand how depression treatment actually works from a clinical perspective, this is the podcast to listen to. Hosted by psychiatrist Chris Aiken, MD and psychiatric nurse practitioner Kellie Newsome, the show delivers practical updates on psychiatric science in a format that is surprisingly accessible for a show aimed at clinicians. The Carlat Psychiatry Podcast covers psychopharmacology, therapy modalities, and treatment strategies with a bias-conscious approach. Episodes on treatment-resistant depression, the mechanics of antidepressant medications, and newer interventions like ketamine therapy are particularly strong. The "Wounded Healers" series profiles influential psychiatrists who have shaped how we understand and treat depression -- figures like Marsha Linehan, who developed DBT while managing her own mental health challenges. The "Hidden Gems" segments spotlight underused treatments that often get overlooked in standard care. The weekly episodes come with CME post-tests, which tells you something about the rigor here. This is not self-help advice dressed up as science. It is actual psychiatric education made available to anyone willing to listen. The scripted delivery style is a fair criticism -- it can feel a bit rehearsed compared to more conversational shows. But the trade-off is precision. When Chris and Kellie explain why a particular medication works or does not work for depression, they cite specific research and acknowledge the limitations honestly. With a 4.7-star rating from over 500 reviews, the show has earned real trust from both professionals and patients who want to understand their treatment better.